T 863 - Names and Identifiers
Name | DGAT-3
|
Synonyms | T 863 T-863 DGAT-3 CS-120 trans-4-[4-(4-Amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]cyclohexaneacetic acid trans-2-(4-(4-(4-aMino-7,7-diMethyl-7H-pyriMido[4,5-b][1,4]oxazin-6-yl)phenyl)cyclohexyl)acetic acid Mino-7,7-diMethyl-2-((1r,4r)-4-(4-(4-a7H-pyriMido[4,5-b][1,4]oxazin-6-yl)phenyl)cyclohexyl)acetic acid Cyclohexaneacetic acid, 4-[4-(4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)phenyl]-, trans- 2-((1,4-trans)-4-(4-(4-Amino-7,7-dimethyl-7H-pyrimido[4,5-b][1,4]oxazin-6-yl)- phenyl)cyclohexyl)acetic acid
|
CAS | 701232-20-4
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T 863 - Physico-chemical Properties
Molecular Formula | C22H26N4O3
|
Molar Mass | 394.47 |
Density | 1.36±0.1 g/cm3(Predicted) |
Boling Point | 616.6±55.0 °C(Predicted) |
Solubility | DMSO: soluble15mg/mL (clear solution) |
Appearance | powder |
Color | white to beige |
pKa | 4.72±0.10(Predicted) |
Storage Condition | 2-8°C |
T 863 - Risk and Safety
T 863 - Preparation solution concentration reference
| 1mg | 5mg | 10mg |
---|
1 mM | 2.535 ml | 12.675 ml | 25.35 ml |
5 mM | 0.507 ml | 2.535 ml | 5.07 ml |
10 mM | 0.254 ml | 1.268 ml | 2.535 ml |
5 mM | 0.051 ml | 0.254 ml | 0.507 ml |
Last Update:2024-01-02 23:10:35
T 863 - Reference Information
Biological activity | T863 (DGAT-3) is an effective and selective Acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1) The oral active inhibitor can act on the acyl-CoA binding site of DGAT1 and inhibit the formation of triacylglycerol mediated by DGAT1. |
Last Update:2024-04-09 22:09:11